Phelorphan
Phelorphan is a purine MTH1 inhibitor identified through chemical array screening. Although it targets cellular MTH1, its cytotoxicity to cancer cells is weaker than that of other reported inhibitors. The cytotoxicity of MTH1 inhibitors may be attributed to off-target effects, and MTH1 is not essential for cancer cell survival.
For research use only. We do not sell to patients.
- CAS No.: 110871-16-4
- Formula: C20H22N2O4S
- Molecular Weight:386.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 110871-16-4
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Molecular Weight 386.46
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Formula C20H22N2O4S
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SMILES
O=C([C@@H](NC([C@@H](NC(CS)=O)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)