76-38-0
Chemical Structure
Methoxyflurane
Synonym(s): DA-759
- CAS No.: 76-38-0
- Formula:C3H4Cl2F2O
- Molecular Weight:164.97
IUPAC Name: 2,2-dichloro-1,1-difluoro-1-methoxyethane
InChIKey: RFKMCNOHBTXSMU-UHFFFAOYSA-N
SMILES: COC(F)(F)C(Cl)Cl
Biological Activity: Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation[1]. Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain[2].
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Methoxyflurane | 98.0% | Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation. Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain. | ||||||||||||||||||||
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- [1]. Mercadante S, et al. Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA).Adv Ther. 2019 Nov;36(11):3030-3046. [Content Brief]
- [2]. NCI Drug Dictionary.methoxyflurane
Keywords
