77-37-2
77-37-2
Chemical Structure
Procyclidine
Synonym(s): Tricyclamol; (±)-Procyclidine
- CAS No.: 77-37-2
- Formula:C19H29NO
- Molecular Weight:287.44
IUPAC Name: 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
InChIKey: WYDUSKDSKCASEF-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCC3
Biological Activity: Procyclidine (Tricyclamol; (±)-Procyclidine), an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].
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Procyclidine | Procyclidine (Tricyclamol; (±)-Procyclidine), an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy. | |||||||||||||||||||||
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References
- [1]. Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11(1):15-21. [Content Brief]
- [2]. Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28(12):2199-208. [Content Brief]
