7772-98-7
Chemical Structure
Sodium thiosulfate (99%, water≤1.0%)
Synonym(s): Sodium hyposulfite (99%, water≤1.0%)
- CAS No.: 7772-98-7
- Formula:Na2S2O3
- Molecular Weight:158.11
InChIKey: HHYVWQYVYKODBB-UHFFFAOYSA-N
SMILES: [Na][Na].O=S(=O)=S=O
Biological Activity: Sodium thiosulfate (Sodium hyposulfite) is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease[1][2][3][4][5][6][7][8][9].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Sodium thiosulfate (99%, water≤1.0%) | 99.89% | Sodium thiosulfate (Sodium hyposulfite) is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Sodium thiosulfate (98%) | 98.30% | Sodium thiosulfate (Sodium hyposulfite) is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Ota A, et al. The selective cytotoxicity of silver thiosulfate, a silver complex, on MCF-7 breast cancer cells through ROS-induced cell death. Pharmacol Rep. 2021 Jun;73(3):847-857. [Content Brief]
- [2]. Macabrey D, et al. Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization. Front Cardiovasc Med. 2022 Oct 3;9:965965. [Content Brief]
- [3]. Nasi S, et al. Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis. PLoS One. 2016 Jul 8;11(7):e0158196. [Content Brief]
- [4]. Lee M, et al. Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. J Neuroinflammation. 2016 Feb 8;13:32. [Content Brief]
- [5]. Sakaguchi M, et al. Sodium thiosulfate attenuates acute lung injury in mice. Anesthesiology. 2014 Dec;121(6):1248-57. [Content Brief]
- [6]. Mizuta Y, et al. Sodium thiosulfate prevents doxorubicin-induced DNA damage and apoptosis in cardiomyocytes in mice. Life Sci. 2020 Sep 15;257:118074. [Content Brief]
- [7]. Bijarnia RK, et al. Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats. PLoS One. 2015 Apr 30;10(4):e0124881. [Content Brief]
- [8]. Wang D, et al. Sodium thiosulfate inhibits epithelial-mesenchymal transition in melanoma via regulating the Wnt/β-catenin signaling pathway. J Dermatol Sci. 2023 Feb;109(2):89-98. [Content Brief]
- [9]. Acero G, et al. Sodium thiosulphate attenuates brain inflammation induced by systemic lipopolysaccharide administration in C57BL/6J mice. Inflammopharmacology. 2017 May 19. [Content Brief]
