80404-23-5
80404-23-5
Chemical Structure
Apocynin-d3
Synonym(s): Acetovanillone-d3
- CAS No.: 80404-23-5
- Formula:C9H7D3O3
- Molecular Weight:169.19
IUPAC Name: 1-(4-hydroxy-3-(methoxy-d3)phenyl)ethan-1-one
InChIKey: DFYRUELUNQRZTB-BMSJAHLVSA-N
SMILES: [2H]C([2H])([2H])OC1=CC(C(C)=O)=CC=C1O
Biological Activity: Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4].
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Apocynin-d3 | Apocynin-d3 is the deuterium labeled Apocynin. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM. | |||||||||||||||||||||
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Apocynin (Standard) | ≥98% | Apocynin (Standard) is the analytical standard of Apocynin. This product is intended for research and analytical applications. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM. Apocynin improves acute lung inflammation in Carrageenan (HY-125474)-induced pleurisy mice model. Apocynin can also be used for cancer research. Apocynin reverses the aging process in mesenchymal stem cells to promote osteogenesis and increases bone mass. | ||||||||||||||||||||
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Apocynin | 99.93% | Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM. Apocynin improves acute lung inflammation in Carrageenan (HY-125474)-induced pleurisy mice model. Apocynin can also be used for cancer research. Apocynin reverses the aging process in mesenchymal stem cells to promote osteogenesis and increases bone mass. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102. [Content Brief]
- [3]. Stefanska J, et al. Mediators Inflamm, 2008, 106507. [Content Brief]
- [4]. Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 181(5):636-48. [Content Brief]
