80875-98-5
80875-98-5
Chemical Structure
(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid
- CAS No.: 80875-98-5
- Formula:C9H15NO2
- Molecular Weight:169.22
IUPAC Name: (2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid
InChIKey: CQYBNXGHMBNGCG-FXQIFTODSA-N
SMILES: OC([C@H](C[C@@]12[H])N[C@]1(CCCC2)[H])=O
Biological Activity: (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a bicyclic hydrophobic proline analog that acts as a polyproline-II helix stabilizer. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid serves as a structural component of Perindopril (HY-B0130). (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid can be used in studies related to organic synthesis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid | 98.0% | (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a bicyclic hydrophobic proline analog that acts as a polyproline-II helix stabilizer. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid serves as a structural component of Perindopril (HY-B0130). (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid can be used in studies related to organic synthesis. | ||||||||||||||||||||
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(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (Standard) | ≥98% | (2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (Standard) is the analytical standard of (2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (HY-20302). This product is intended for research and analytical applications. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a bicyclic hydrophobic proline analog that acts as a polyproline-II helix stabilizer. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid serves as a structural component of Perindopril (HY-B0130). (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid can be used in studies related to organic synthesis. | ||||||||||||||||||||
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References
- [1]. Kubyshkin V, et al. Construction of a polyproline structure with hydrophobic exterior using octahydroindole-2-carboxylic acid. Organic & biomolecular chemistry. 2017 Jan 18;15(3):619-627.
- [2]. Sayago FJ, et al. A straightforward route to enantiopure alpha-substituted derivatives of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. Tetrahedron. 2009 Jul 01;65(27):5174-5180. [Content Brief]
- [3]. Kubyshkin V. Exploring hydrophobicity limits of polyproline helix with oligomeric octahydroindole‑2‑carboxylic acid[J]. Journal of Peptide Science, 2018, 24(4‑5): e3076.
