82186-77-4
82186-77-4
Chemical Structure
Lumefantrine
Synonym(s): Benflumetol
- CAS No.: 82186-77-4
- Formula:C30H32Cl3NO
- Molecular Weight:528.94
IUPAC Name: (Z)-2-(dibutylamino)-1-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethan-1-ol
InChIKey: DYLGFOYVTXJFJP-MYYYXRDXSA-N
SMILES: OC(CN(CCCC)CCCC)C1=CC(Cl)=CC(/C2=C\C3=CC=C(Cl)C=C3)=C1C4=C2C=C(Cl)C=C4
Biological Activity: Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity[1][2].
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Lumefantrine | 99.40% | Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity. | ||||||||||||||||||||
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Lumefantrine (Standard) | ≥98% | Lumefantrine (Standard) is the analytical standard of Lumefantrine. This product is intended for research and analytical applications. Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug. | ||||||||||||||||||||
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Lumefantrine-d18 | Lumefantrine-d18 is the deuterium labeled Lumefantrine, which is an antimalarial agent. | |||||||||||||||||||||
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Lumefantrine-d9 | 97.03% | Lumefantrine-d9 is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs. | ||||||||||||||||||||
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References
- [1]. Yufan Ma, et al. Enhanced antimalarial activity by a novel artemether-lumefantrine lipid emulsion for parenteral administration. Antimicrob Agents Chemother. 2014 Oct;58(10):5658-65. [Content Brief]
- [2]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423. [Content Brief]
