85-66-5
85-66-5
Chemical Structure
Pyocyanin
Synonym(s): Pyocyanine; Sanazin; Sanasin
- CAS No.: 85-66-5
- Formula:C13H10N2O
- Molecular Weight:210.23
IUPAC Name: 5-methylphenazin-1(5H)-one
InChIKey: YNCMLFHHXWETLD-UHFFFAOYSA-N
SMILES: O=C1C=CC=C2N(C3=C(C=CC=C3)N=C21)C
Biological Activity: Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity[1][2][3][4].
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Pyocyanin | 99.23% | Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity. | ||||||||||||||||||||
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Pyocyanin (Standard) | ≥98% | Pyocyanin (Standard) is the analytical standard of Pyocyanin. This product is intended for research and analytical applications. Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity. | ||||||||||||||||||||
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References
- [1]. Paulina Castañeda-Tamez, et al. Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa. Front Microbiol. 2018 Jun 27;9:1348. [Content Brief]
- [2]. Marreiro de Sales-Neto J, et al. Anti-inflammatory potential of pyocyanin in LPS-stimulated murine macrophages. Immunopharmacol Immunotoxicol. 2019 Feb;41(1):102-108. [Content Brief]
- [3]. Kamer AMA, et al. Antibacterial, antibiofilm, and anti-quorum sensing activities of pyocyanin against methicillin-resistant Staphylococcus aureus: in vitro and in vivo study. BMC Microbiol. 2023 Apr 24;23(1):116. [Content Brief]
- [4]. Arora D, et al. Pyocyanin induces systemic oxidative stress, inflammation and behavioral changes in vivo. Toxicol Mech Methods. 2018 Jul;28(6):410-414. [Content Brief]
