852391-19-6
852391-19-6
Chemical Structure
Necrostatin 2
- CAS No.: 852391-19-6
- Formula:C13H12ClN3O2
- Molecular Weight:277.71
IUPAC Name: (R)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione
InChIKey: WIKGAEMMNQTUGL-SNVBAGLBSA-N
SMILES: ClC1=C2C(C(C[C@@H]3C(N(C)C(N3)=O)=O)=CN2)=CC=C1
Biological Activity: Necrostatin 2 is a potent necroptosis inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. Necrostatin 2 is also a RIPK1 inhibitor.
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Necrostatin 2 | 99.78% | Necrostatin 2 is a potent necroptosis inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. Necrostatin 2 is also a RIPK1 inhibitor. | ||||||||||||||||||||
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Keywords
