856243-80-6
Chemical Structure
Degrasyn
Synonym(s): WP1130
- CAS No.: 856243-80-6
- Formula:C19H18BrN3O
- Molecular Weight:384.27
IUPAC Name: (S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide
InChIKey: LIDOPKHSVQTSJY-VMEIHUARSA-N
SMILES: BrC1=CC=CC(/C=C(C(N[C@H](C2=CC=CC=C2)CCC)=O)\C#N)=N1
Biological Activity: Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2.
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Degrasyn | 99.70% | Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2. | ||||||||||||||||||||
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Keywords