897771-47-0
Chemical Structure
DC-5163
- CAS No.: 897771-47-0
- Formula:C18H20ClN3OS
- Molecular Weight:361.89
IUPAC Name: 3-benzyl-N-(3-chloro-4-methoxyphenyl)imidazolidine-1-carbothioamide
InChIKey: MWYSGSPJSNOODI-UHFFFAOYSA-N
SMILES: S=C(N1CCN(CC2=CC=CC=C2)C1)NC3=CC=C(OC)C(Cl)=C3
Biological Activity: DC-5163 is a potent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with an IC50 of 176.3 nM and a Kd of 3.192 μM. DC-5163 can inhibit glycolysis pathway partially. DC-5163 also selectively inhibits cancer cell proliferation and induces apoptosis[1].
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DC-5163 | 99.30% | DC-5163 is a potent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with an IC50 of 176.3 nM and a Kd of 3.192 μM. DC-5163 can inhibit glycolysis pathway partially. DC-5163 also selectively inhibits cancer cell proliferation and induces apoptosis. | ||||||||||||||||||||
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Keywords