92-13-7
92-13-7
Chemical Structure
Pilocarpine
- CAS No.: 92-13-7
- Formula:C11H16N2O2
- Molecular Weight:208.26
IUPAC Name: (3S,4R)-3-ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydrofuran-2(3H)-one
InChIKey: QCHFTSOMWOSFHM-WPRPVWTQSA-N
SMILES: O=C1OC[C@H](CC2=CN=CN2C)[C@@H]1CC
Biological Activity: Pilocarpine is an orally active, selective M3 muscarinic acetylcholine receptor agonist. Pilocarpine can induce seizures. Pilocarpine is used in research on conditions such as epilepsy, dry mouth (xerostomia), and elevated intraocular pressure[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pilocarpine | 99.89% | Pilocarpine is an orally active, selective M3 muscarinic acetylcholine receptor agonist. Pilocarpine can induce seizures. Pilocarpine is used in research on conditions such as epilepsy, dry mouth (xerostomia), and elevated intraocular pressure. | ||||||||||||||||||||
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Pi-Methylimidazoleacetic acid | Pi-Methylimidazoleacetic acid is a potential neurotoxin. | |||||||||||||||||||||
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Pi-Methylimidazoleacetic acid hydrochloride | 99.01% | Pi-Methylimidazoleacetic acid hydrochloride is a potential neurotoxin. | ||||||||||||||||||||
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3-Methylhistamine dihydrochloride (Standard) | ≥98% | 3-Methylhistamine (dihydrochloride) (Standard) is the analytical standard of 3-Methylhistamine (dihydrochloride). This product is intended for research and analytical applications. 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice. | ||||||||||||||||||||
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1-Methylimidazoleacetic acid (Standard) | ≥98% | 1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) (Standard) is the analytical standard of 1-Methylimidazoleacetic acid. This product is intended for research and analytical applications. 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis. | ||||||||||||||||||||
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5-Chloromethyl-1-propyl-1H-imidazole hydrochloride | 95.0% | 5-Chloromethyl-1-propyl-1H-imidazole hydrochloride is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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H-His(1-Me)-OMe | H-His(1-Me)-OMe is a histidine derivative that can be used for amino acid synthesis. | |||||||||||||||||||||
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1-Methyl-L-histidine | 99.97% | 1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake. | ||||||||||||||||||||
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3-Methyl-L-histidine (Standard) | 99.99% | 3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin. | ||||||||||||||||||||
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1-Methylhistamine dihydrochloride (Standard) | 98.40% | 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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1-Methyl-4-imidazoleacetic acid hydrochloride | 98.0% | 1-Methyl-4-imidazoleacetic acid hydrochloride is a stable metabolite of Histamine (HY-B1204) that is produced by the oxidation of the primary metabolite, N-methylhistamine. | ||||||||||||||||||||
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References
- [1]. Matsuzaki K, et al. Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands. FEBS Open Bio. 2017 Dec 7;8(1):85-93. [Content Brief]
- [2]. Yuan XL, et al. Cytotoxicity of pilocarpine to human corneal stromal cells and its underlying cytotoxic mechanisms. Int J Ophthalmol. 2016 Apr 18;9(4):505-11. [Content Brief]
- [3]. Tonta MA, et al. Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium. Br J Pharmacol. 1994 Jun;112(2):525-32. [Content Brief]
- [4]. Manuela Mazzuferi, et al. Rapid epileptogenesis in the mouse pilocarpine model: Video-EEG, pharmacokinetic and histopathological characterization. Experimental Neurology.
