92-78-4
92-78-4
Chemical Structure
Naphthol AS-E
- CAS No.: 92-78-4
- Formula:C17H12ClNO2
- Molecular Weight:297.74
IUPAC Name: N-(4-chlorophenyl)-3-hydroxy-2-naphthamide
InChIKey: OHAXNCGNVGGWSO-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=C2C=CC=CC2=C1)NC3=CC=C(Cl)C=C3
Biological Activity: Naphthol AS-E is a potent and cell-permeable inhibitor of KIX-KID interaction. Naphthol AS-E directly binds to the KIX domain of CBP (Kd:8.6 μM), blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2.26 μM. Naphthol AS-E can be used for cancer research.
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Naphthol AS-E | 98.0% | Naphthol AS-E is a potent and cell-permeable inhibitor of KIX-KID interaction. Naphthol AS-E directly binds to the KIX domain of CBP (Kd:8.6 μM), blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2.26 μM. Naphthol AS-E can be used for cancer research. | ||||||||||||||||||||
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Naphthol AS-E (Standard) | ≥98% | Naphthol AS-E (Standard) is the analytical standard of Naphthol AS-E (HY-104068). This product is intended for research and analytical applications. Naphthol AS-E is a potent and cell-permeable inhibitor of KIX-KID interaction. Naphthol AS-E directly binds to the KIX domain of CBP (Kd:8.6 μM), blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2.26 μM. Naphthol AS-E can be used for cancer research. | ||||||||||||||||||||
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