92-85-3
Chemical Structure
Thianthrene
- CAS No.: 92-85-3
- Formula:C12H8S2
- Molecular Weight:216.33
IUPAC Name: Thianthrene
InChIKey: GVIJJXMXTUZIOD-UHFFFAOYSA-N
SMILES: C12=CC=CC=C1SC3=C(C=CC=C3)S2
Biological Activity: Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani (IC50 = 23 μM). Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thianthrene | 99.97% | Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani (IC50 = 23 μM). Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thianthrene (Standard) | ≥98% | Thianthrene (Standard) is the analytical standard of Thianthrene. This product is intended for research and analytical applications. Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani (IC50 = 23 μM). Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.76
HY-Y0055RPhenothiazine (Standard) -
Similarity Score 0.67
HY-W016174Diphenyl sulfide -
Similarity Score 0.66
HY-Y17492-Chlorophenothiazine -
Similarity Score 0.66
HY-W777535Naphthalene-13C10 -
Similarity Score 0.66
HY-W777535SNaphthalene-sup>13C6 -
Similarity Score 0.66
HY-B1727RPhenanthrene (Standard) -
Similarity Score 0.66
HY-W777456Phenanthrene-13C6 -
Similarity Score 0.66
HY-W777457Anthracene-13C6 -
Explore the MedChemAI to find more analogs