924641-59-8
924641-59-8
Chemical Structure
AZD5597
- CAS No.: 924641-59-8
- Formula:C23H28FN7O
- Molecular Weight:437.51
IUPAC Name: (S)-(4-((5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone
InChIKey: NTSDIJMNXYJJNG-SFHVURJKSA-N
SMILES: CC(N1C(C2=NC(NC3=CC=C(C=C3)C(N4C[C@H](CC4)NC)=O)=NC=C2F)=CN=C1C)C
Biological Activity: AZD5597 is an inhibitor of CDK with IC50 values of both 2 nM for CDK1 and CDK2. AZD5597 can inhibit the proliferation of tumor cells and has anti-tumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD5597 | 98.9% | AZD5597 is an inhibitor of CDK with IC50 values of both 2 nM for CDK1 and CDK2. AZD5597 can inhibit the proliferation of tumor cells and has anti-tumor activity. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.58
HY-10012AZD-5438 -
Similarity Score 0.52
HY-112243Cimpuciclib -
Similarity Score 0.52
HY-151575PfGSK3/PfPK6-IN-2 -
Similarity Score 0.50
HY-130247Flonoltinib -
Similarity Score 0.50
HY-180574TSL2109 -
Similarity Score 0.50
HY-128669Abemaciclib metabolite M2 -
Similarity Score 0.49
HY-143444JAK-IN-20 -
Similarity Score 0.49
HY-153712JAK-IN-28 -
Similarity Score 0.49
HY-153949YK-2-69 -
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