944258-89-3
944258-89-3
Chemical Structure
Simotinib
- CAS. Nr.: 944258-89-3
- Formula:C25H26ClFN4O4
- Molecular Weight:500.95
IUPAC Name: 6-(2-(5,8-dioxa-10-azadispiro[2.0.44.33]undecan-10-yl)ethoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
InChIKey: OXWUWXCJDBRCCG-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C(NC(C=C3)=CC(Cl)=C3F)=NC=N2)C=C1OCCN4CC5(CC5)C6(OCCO6)C4
Biological Activity: Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities[1].
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Simotinib | 99.39% | Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities. | ||||||||||||||||||||
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Simotinib (Standard) | ≥98% | Simotinib (Standard) is the analytical standard of Simotinib. This product is intended for research and analytical applications. Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities. | ||||||||||||||||||||
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