950-99-2
950-99-2
Chemical Structure
2,2,5,7,8-Pentamethyl-6-Chromanol
Synonym(s): PMC
- No. CAS: 950-99-2
- Formula:C14H20O2
- Molecular Weight:220.31
IUPAC Name: 2,2,5,7,8-pentamethylchroman-6-ol
InChIKey: SEBPXHSZHLFWRL-UHFFFAOYSA-N
SMILES: OC1=C(C)C(C)=C2C(CCC(C)(C)O2)=C1C
Biological Activity: 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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2,2,5,7,8-Pentamethyl-6-Chromanol | 99.30% | 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. | ||||||||||||||||||||
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2,2,5,7,8-Pentamethyl-6-Chromanol (Standard) | ≥98% | 2,2,5,7,8-Pentamethyl-6-Chromanol (Standard) is the analytical standard of 2,2,5,7,8-Pentamethyl-6-Chromanol. This product is intended for research and analytical applications. 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. | ||||||||||||||||||||
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(R)-Trolox (Standard) | ≥98% | (R)-Trolox (Standard) is the analytical standard of (R)-Trolox (HY-101445A). This product is intended for research and analytical applications. (R)-Trolox is a vitamin E analogue and a competitive tyrosinase inhibitor with a Ki value of 0.83 mM and a ID50 value of 1.88 mM. The (R)-Trolox has stronger tyrosinase affinity than the (S) enantiomer (Ki value of 0.61 mM). | ||||||||||||||||||||
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(S)-Trolox (Standard) | ≥98% | (S)-Trolox (Standard) is the analytical standard of (S)-Trolox (HY-101445B). This product is intended for research and analytical applications. (S)-Trolox is an analogue of vitamin E, in which the phytyl chain is replaced with a carboxyl group. (S)-Trolox is frequently used as a model compound for studies of structural features, as well as a standard for evaluation of antioxidant activity. (S)-Trolox has potent and specific neuroprotective and antioxidant effects. | ||||||||||||||||||||
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Trolox (GMP) | Trolox (GMP) is Trolox (HY-101445) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage. | |||||||||||||||||||||
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γ-CEHC | 99.20% | γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide. | ||||||||||||||||||||
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alpha-CEHC | 99.3% | alpha-CEHC is a water-soluble metabolite of alpha-tocopherol (α-TOH) with potential antioxidant activity. alpha-CEHC slightly inhibits macrophage-induced low-density lipoprotein (LDL) oxidation, and its inhibitory potency is concentration-dependent. | ||||||||||||||||||||
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(±)-α-CMBHC | (±)-α-CMBHC is a metabolite of α-Tocopherol. | |||||||||||||||||||||
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rel-α-Vitamin E | 70.0% | rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture. | ||||||||||||||||||||
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2-ambo-Vitamin E-13C6 | α-Vitamin E-13C6 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant. | |||||||||||||||||||||
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2-ambo-Vitamin E-13C3 | α-Vitamin E-13C3 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant. | |||||||||||||||||||||
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DL-alpha-Tocopherol | 98.96% | DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB. | ||||||||||||||||||||
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