950365-31-8
950365-31-8
Chemical Structure
GPX4 activator 2
- CAS No.: 950365-31-8
- Formula:C20H26N6O2S
- Molecular Weight:414.52
InChIKey: WOSPZXZOWHOQTI-UHFFFAOYSA-N
SMILES: CN(CC1)CCN1C2=NN=C(S2)N3C=CC=C3CNC4=CC=C(OC)C=C4OC
Biological Activity: GPX4 activator 2 is a GPX4 activator with a Ka value of 0.426 μM for human GPX4. GPX4 activator 2 reduces lipid hydroperoxide levels, prevents lipid peroxide accumulation, and inhibits ferroptosis. GPX4 activator 2 rescues cell death induced by Erastin (HY-15763). GPX4 activator 2 exerts cardioprotective effects in a mouse model of doxorubicin (HY-15142A)-induced myocardial injury[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GPX4 activator 2 | 99.23% | GPX4 activator 2 is a GPX4 activator with a Ka value of 0.426 μM for human GPX4. GPX4 activator 2 reduces lipid hydroperoxide levels, prevents lipid peroxide accumulation, and inhibits ferroptosis. GPX4 activator 2 rescues cell death induced by Erastin (HY-15763). GPX4 activator 2 exerts cardioprotective effects in a mouse model of doxorubicin (HY-15142A)-induced myocardial injury. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-161928GPX4 activator 1 -
Similarity Score 0.48
HY-177315Cathepsin K-IN-8 -
Similarity Score 0.47
HY-19347WDR5-0103 -
Similarity Score 0.47
HY-121392GR 125743 -
Similarity Score 0.47
HY-118336VUF10497 -
Similarity Score 0.47
HY-15379Atevirdine -
Similarity Score 0.46
HY-147316TP-5801 -
Similarity Score 0.46
HY-176941ALK2-IN-6 -
Similarity Score 0.46
HY-105097Atevirdine mesylate -
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