97938-31-3
97938-31-3
Chemical Structure
Leachianone A
- CAS No.: 97938-31-3
- Formula:C26H30O6
- Molecular Weight:438.51
IUPAC Name: (S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one
InChIKey: YLTPWCZXKJSORQ-GYCJOSAFSA-N
SMILES: O=C1C[C@@H](C2=CC=C(O)C=C2OC)OC3=C(C[C@H](C(C)=C)C/C=C(C)\C)C(O)=CC(O)=C13
Biological Activity: Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent[1]. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Leachianone A | 99.44% | Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways. | ||||||||||||||||||||
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References
- [1]. Jeong GS, et al. Lavandulyl flavanones from Sophora flavescens protect mouse hippocampal cells against glutamate-induced neurotoxicity via the induction of heme oxygenase-1. Biol Pharm Bull. 2008 Oct;31(10):1964-7. [Content Brief]
- [2]. Cheung CS, et al. Leachianone A as a potential anti-cancer drug by induction of apoptosis in human hepatoma HepG2 cells. Cancer Lett. 2007 Aug 18;253(2):224-35. Epub 2007 Mar 26. [Content Brief]
Keywords
