98299-40-2
98299-40-2
Chemical Structure
Hexahydrosiladifenidol
- CAS No.: 98299-40-2
- Formula:C20H33NOSi
- Molecular Weight:331.57
InChIKey: QTBCATBNRIYMPB-UHFFFAOYSA-N
SMILES: O[Si](CCCN1CCCCC1)(C2CCCCC2)C3=CC=CC=C3
Biological Activity: Hexahydrosiladifenidol is a muscarinic receptor antagonist. Hexahydrosiladifenidol blocks sympathetic ganglion M1 and brainstem M2 muscarinic receptors[1][2][3].
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Hexahydrosiladifenidol | Hexahydrosiladifenidol is a muscarinic receptor antagonist. Hexahydrosiladifenidol blocks sympathetic ganglion M1 and brainstem M2 muscarinic receptors. | |||||||||||||||||||||
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References
- [1]. Baudiere B, et al. Characterization of the muscarinic receptor subtype in isolated gastric fundic cells of the rabbit. Biochemical pharmacology. 1987 Sep 15;36(18):2957-61.
- [2]. Murphy NP, et al. Potassium- and carbachol-evoked release of [3H]noradrenaline from human neuroblastoma cells, SH-SY5Y. Journal of neurochemistry. 1991 May;56(5):1810-5.
- [3]. Fuder H, et al. Organ selectivity of hexahydrosiladifenidol in blocking pre- and postjunctional muscarinic receptors studied in guinea-pig ileum and rat heart. European journal of pharmacology. 1985 Jul 11;113(1):125-7. [Content Brief]
