99-43-4
Chemical Structure
Oxybuprocaine
Synonym(s): Benoxinate; Novesinol; Oxybucaine
- CAS No.: 99-43-4
- Formula:C17H28N2O3
- Molecular Weight:308.42
IUPAC Name: 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate
InChIKey: CMHHMUWAYWTMGS-UHFFFAOYSA-N
SMILES: O=C(OCCN(CC)CC)C1=CC=C(N)C(OCCCC)=C1
Biological Activity: Oxybuprocaine is a short-acting ester anesthetic. Oxybuprocaine binds to sodium channels and reversibly stabilizes neuronal membranes. Oxybuprocaine has cutaneous analgesic properties. Oxybuprocaine is less potent than Bupivacaine (HY-B0405) at producing central nervous system and cardiovascular toxicity. Oxybuprocaine can be used in ophthalmology and otolaryngology[1][2][3][4][5][6].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Oxybuprocaine | 99.93% | Oxybuprocaine is a short-acting ester anesthetic. Oxybuprocaine binds to sodium channels and reversibly stabilizes neuronal membranes. Oxybuprocaine has cutaneous analgesic properties. Oxybuprocaine is less potent than Bupivacaine (HY-B0405) at producing central nervous system and cardiovascular toxicity. Oxybuprocaine can be used in ophthalmology and otolaryngology. | ||||||||||||||||||||
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- [1]. Masayuki Kohsaka, et al. Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo-controlled pilot trial. Mov Disord [Content Brief]
- [2]. Nam SM, et al. Comparison of corneal thickness after the instillation of topical anesthetics: proparacaine versus oxybuprocaine. Cornea. 2006 Jan;25(1):51-4. [Content Brief]
- [3]. Tomaciello F, et al. Resveratrol lacks protective activity against acute seizures in mouse models. Neurosci Lett. 2016 Oct 6;632:199-203. [Content Brief]
- [4]. Hung CH, et al. The systemic toxicity of equipotent proxymetacaine, oxybuprocaine, and bupivacaine during continuous intravenous infusion in rats. Anesth Analg. 2010 Jan 1;110(1):238-42. [Content Brief]
- [5]. Mirković I, et al. Pentadecapeptide BPC 157 shortens duration of tetracaine-and oxybuprocaine-induced corneal anesthesia in rats. Acta Clinica Croatica, 2020, 59(3): 394.
- [6]. Dong Z, et al. Efficacy and Safety of Oxybuprocaine Hydrochloride Gel in Alleviating Pain during Male Urethral Catheterization: A Single-Center Randomized Controlled Study. Int J Clin Pract. 2022 Sep 14;2022:5734387. [Content Brief]
Keywords
