2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. Cbl-b-IN-8

Cbl-b-IN-8 (Compound 293) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.5 nM and 7.8 nM, respectively.

For research use only. We do not sell to patients.

Cbl-b-IN-8 Chemical Structure

Cbl-b-IN-8 Chemical Structure

CAS No. : 2815223-33-5

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Cbl-b-IN-8 Related Antibodies

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Description

Cbl-b-IN-8 (Compound 293) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.5 nM and 7.8 nM, respectively[1].

IC50 & Target

IC50: 5.5 nM (Cbl-b), 7.8 nM (c-Cbl)[1]
Molecular Weight

667.76

Formula

C35H44F3N7O3
CAS No.
SMILES

O=C1C2=CC(CN3[C@H](CN(CC3)C)C(C)C)=CC(C(F)(F)F)=C2CN1C4=CC(C5(COC5)CC6=NN=CN6C)=CC(OC7CCCC7)=N4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cbl-b-IN-8 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cbl-b-IN-82815223-33-5E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligasecasitas B-lineage lymphoma-bInhibitorinhibitorinhibit

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