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Cat. No.: HY-161829

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CDK7 ligand 1

CDK7 ligand 1 is an active control ligand for CDK7 ligand 2 (HY-161830). CDK7 ligand 2 is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Formula: C₂₅H₂₉IN₆O₂
Molecular Weight:572.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

CDK7 ligand 1 Chemical Structure

Size

Price

Stock

Quantity

Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CDK7 ligand 1 is an active control ligand for CDK7 ligand 2 (HY-161830). CDK7 ligand 2 is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs^[1].

Chemical Information

Molecular Weight 572.44
Formula C₂₅H₂₉IN₆O₂
SMILES

O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(I)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7). European Journal of Medicinal Chemistry (2024): 116613. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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