2. PROTAC
  3. Ligands for E3 Ligase
  4. Cereblon ligand-5

Cereblon ligand-5 is a cereblon ligand that recruits the CRBN protein. Cereblon ligand-5 can be linked to the BTK target protein ligand via a linker to form PROTAC BTK Degrader-15 (HY-182910).

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Cereblon ligand-5

Cereblon ligand-5 Chemical Structure

CAS No. : 4543-39-9

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Cereblon ligand-5 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

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Description

Cereblon ligand-5 is a cereblon ligand that recruits the CRBN protein. Cereblon ligand-5 can be linked to the BTK target protein ligand via a linker to form PROTAC BTK Degrader-15 (HY-182910)[1].

IC50 & Target[1]

Cereblon

 

In Vitro

Cereblon ligand-5 can be linked to the BTK target protein ligand via a linker to form PROTAC BTK Degrader-15 (HY-182910). PROTAC BTK Degrader-15 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cereblon ligand-5 Related Antibodies
Molecular Weight

125.13

Formula

C6H7NO2
CAS No.
SMILES

O=C(N1)C2CC(C2)C1=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cereblon ligand-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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Cereblon ligand-5
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HY-182911
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