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CGS 21680 sodium

14 Cited Publications
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Based on 14 publication(s) in Google Scholar

CGS 21680 (sodium) is a biochemical assay reagent.

For research use only. We do not sell to patients.

  • CAS No.: 120225-64-1
  • Formula: C23H28N7NaO6
  • Molecular Weight:521.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • CGS 21680 sodium Chemical Structure
    CGS 21680 sodium Chemical Structure
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
  • Experimental Validation Results for CGS 21680 sodium
CAS No.: 120225-64-1
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  • CGS 21680 sodium Chemical Structure
    CGS 21680 sodium Chemical Structure
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    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: Nature. 2026 Jan;649(8096):423-431. [Abstract]

    Customer Validation
     Immobility time in forced swimming test 30 minutes after intraperitoneal (i.p.) injection of an A1 receptor agonist (CHA; 0.1 mg/kg) or an A2A receptor agonist (CGS 21680 Hydrochloride; 0.1 mg/kg) in chronic restraint stress (CRS) mice.

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: Nature. 2026 Jan;649(8096):423-431. [Abstract]

    Customer Validation
     Twenty-four hours after intraperitoneal injection of CHA or CGS21680 (CGS 21680 Hydrochloride; 0.1 mg/kg) into CRS mice, immobility time and sucrose preference in the forced swimming test were measured.

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: Nature. 2026 Jan;649(8096):423-431. [Abstract]

    Customer Validation
     Concentrations of CHA and CGS 21680 Hydrochloride in serum (top) and brain tissue (bottom) at 30 min and 24 h after i.p. injection, measured by LC-MS. Data are mean ± s.e.m.

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: Cell Mol Gastroenterol Hepatol. 2025 May 21:101539. [Abstract]

    Customer Validation
     Percentage quantification of ASCs after 3 days of treatment with the A2aR agonist CGS 21680 Hydrochloride (1 μM) with or without Inosine (250 μM).

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: J Cell Mol Med. 2025 Mar;29(5):e70458. [Abstract]

    Customer Validation
     Schematic illustration showed that CGS 21680 Hydrochloride (1 mg/kg) or dimethyl sulfoxide (DMSO) was instilled combined with LPS (5 mg/kg) challenge for 24 h.

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: J Cell Mol Med. 2025 Mar;29(5):e70458. [Abstract]

    Customer Validation
     WT and Mac‐A2aR‐KO mice were treated with LPS (5 mg/kg) and CGS 21680 Hydrochloride (1 mg/kg) or PBS for 24 h. Assessment of kidney oedema (n = 3).

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: J Cell Mol Med. 2025 Mar;29(5):e70458. [Abstract]

    Customer Validation
     Intracellular total ROS was detected in PMA‐differentiated THP‐1 cells treated with vehicle, CGS 21680 Hydrochloride (10 nM), LPS (1 μg/mL) or LPS after 30 min CGS 21680 Hydrochloride pretreatment (n = 3).

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: J Cell Mol Med. 2025 Mar;29(5):e70458. [Abstract]

    Customer Validation
     Intracellular total ROS was detected in PMA‐differentiated THP‐1 cells treated with vehicle, LPS (100 μg/mL) and interferon‐gamma (IFN‐γ) (20 ng/mL) with or without 30 min CGS 21680 Hydrochloride pretreatment before; interleukin (IL)‐4 (20 ng/mL) and IL‐13 (20 ng/mL) with or without 30 min CGS 21680 Hydrochloride pretreatment before (n = 3).

  • 1/16

    CGS 21680 sodium purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2023 Jan 1:249:114410. [Abstract]

    Customer Validation
     CGS21680 (10 μM) elevates the expression level of A2aR protein in A549 cells.

  • CGS 21680 sodium