Dixyrazine
Based on 1 Customer Validation
Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.46%
- CAS. Nr.: 2470-73-7
- Formel: C24H33N3O2S
- Molecular Weight:427.60
-
Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Biologische Aktivität
Beschreibung
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 2470-73-7
-
Appearance Solid
-
Molecular Weight 427.60
-
Formel C24H33N3O2S
-
Color White to off-white
-
SMILES
CC(CN1C2=C(C=CC=C2)SC3=CC=CC=C13)CN4CCN(CCOCCO)CC4
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (233.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (272 KB)
-
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
-
Handling Instructions (2659 KB)
Verweise
[1]. Westergren I, et al. Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate. Acta Neurochir (Wien). 1991;113(3-4):171-5. [Content Brief]
[2]. Johansson BB, et al. Phenothiazine-mediated protection of the blood-brain barrier during acute hypertension. Stroke. 1982 Mar-Apr;13(2):220-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3386 mL | 11.6932 mL | 23.3863 mL | 58.4659 mL |
| 5 mM | 0.4677 mL | 2.3386 mL | 4.6773 mL | 11.6932 mL | |
| 10 mM | 0.2339 mL | 1.1693 mL | 2.3386 mL | 5.8466 mL | |
| 15 mM | 0.1559 mL | 0.7795 mL | 1.5591 mL | 3.8977 mL | |
| 20 mM | 0.1169 mL | 0.5847 mL | 1.1693 mL | 2.9233 mL | |
| 25 mM | 0.0935 mL | 0.4677 mL | 0.9355 mL | 2.3386 mL | |
| 30 mM | 0.0780 mL | 0.3898 mL | 0.7795 mL | 1.9489 mL | |
| 40 mM | 0.0585 mL | 0.2923 mL | 0.5847 mL | 1.4616 mL | |
| 50 mM | 0.0468 mL | 0.2339 mL | 0.4677 mL | 1.1693 mL | |
| 60 mM | 0.0390 mL | 0.1949 mL | 0.3898 mL | 0.9744 mL | |
| 80 mM | 0.0292 mL | 0.1462 mL | 0.2923 mL | 0.7308 mL | |
| 100 mM | 0.0234 mL | 0.1169 mL | 0.2339 mL | 0.5847 mL |