Polaprezinc
Based on 1 publication(s) in Google Scholar
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.0%
- CAS. Nr.: 107667-60-7
- Formel: C9H11N4O3Zn
- Molecular Weight:288.59
-
Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Polaprezinc
More
Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS. Nr. 107667-60-7
-
Appearance Solid
-
Molecular Weight 288.59
-
Formel C9H11N4O3Zn
-
Color White to off-white
-
SMILES
O=C1[C@@H]([N-](C2=O)[Zn+2](NCC2)[O-]1)CC3=CN=CN3
-
Synonyms
Zinc L-carnosine
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Adv Sci (Weinh)
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer. [Abstract]2024 Mar;11(9):e2304939. PMID: 38115765
Lösungsmittel & Löslichkeit
1 M HCl : 50 mg/mL (173.26 mM; Need ultrasonic)
H2O : 1 mg/mL (3.47 mM; ultrasonic and adjust pH to 2 with HCl)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Protokoll
Mice[1]
Male C57BL/6J mice (8-weeks-old; weight, ~20 g) are used. The mice are acclimated for 7 days. They are housed 4-5/cage and fed a laboratory rodent pellet formula and tap water ad libitum. Mice are maintained at a constant temperature of 22°C±0.5°C, a humidity of 50%±5% and are exposed to 12 h light/dark cycles. The mice orally receive 100 mg/kg body weight Polaprezinc in the drinking water. The mice are irradiated at a dose rate of ~200 cGy/min using a 150 kVp X-ray unit. For dosimetry, a probe connected to an electrometer system is placed close to the target site.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Reinheit & Dokumentation
-
Data Sheet (275 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 1 M HCl | 1 mM | 3.4651 mL | 17.3256 mL | 34.6512 mL | 86.6281 mL |
| 1 M HCl | 5 mM | 0.6930 mL | 3.4651 mL | 6.9302 mL | 17.3256 mL |
| 10 mM | 0.3465 mL | 1.7326 mL | 3.4651 mL | 8.6628 mL | |
| 15 mM | 0.2310 mL | 1.1550 mL | 2.3101 mL | 5.7752 mL | |
| 20 mM | 0.1733 mL | 0.8663 mL | 1.7326 mL | 4.3314 mL | |
| 25 mM | 0.1386 mL | 0.6930 mL | 1.3860 mL | 3.4651 mL | |
| 30 mM | 0.1155 mL | 0.5775 mL | 1.1550 mL | 2.8876 mL | |
| 40 mM | 0.0866 mL | 0.4331 mL | 0.8663 mL | 2.1657 mL | |
| 50 mM | 0.0693 mL | 0.3465 mL | 0.6930 mL | 1.7326 mL | |
| 60 mM | 0.0578 mL | 0.2888 mL | 0.5775 mL | 1.4438 mL | |
| 80 mM | 0.0433 mL | 0.2166 mL | 0.4331 mL | 1.0829 mL | |
| 100 mM | 0.0347 mL | 0.1733 mL | 0.3465 mL | 0.8663 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Polaprezinc Related Classifications
HY-B0729 Related Classifications
Powered by Bioz