Bis-PEG2-acid
Based on 1 Customer Validation
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 19364-66-0
- Formel: C8H14O6
- Molecular Weight:206.19
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 19364-66-0
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Appearance Solid
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Molecular Weight 206.19
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Formel C8H14O6
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Color White to off-white
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SMILES
O=C(O)CCOCCOCCC(O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (484.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8499 mL | 24.2495 mL | 48.4990 mL | 121.2474 mL |
| 5 mM | 0.9700 mL | 4.8499 mL | 9.6998 mL | 24.2495 mL | |
| 10 mM | 0.4850 mL | 2.4249 mL | 4.8499 mL | 12.1247 mL | |
| 15 mM | 0.3233 mL | 1.6166 mL | 3.2333 mL | 8.0832 mL | |
| 20 mM | 0.2425 mL | 1.2125 mL | 2.4249 mL | 6.0624 mL | |
| 25 mM | 0.1940 mL | 0.9700 mL | 1.9400 mL | 4.8499 mL | |
| 30 mM | 0.1617 mL | 0.8083 mL | 1.6166 mL | 4.0416 mL | |
| 40 mM | 0.1212 mL | 0.6062 mL | 1.2125 mL | 3.0312 mL | |
| 50 mM | 0.0970 mL | 0.4850 mL | 0.9700 mL | 2.4249 mL | |
| 60 mM | 0.0808 mL | 0.4042 mL | 0.8083 mL | 2.0208 mL | |
| 80 mM | 0.0606 mL | 0.3031 mL | 0.6062 mL | 1.5156 mL | |
| 100 mM | 0.0485 mL | 0.2425 mL | 0.4850 mL | 1.2125 mL |
Bis-PEG2-acid Related Classifications
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