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Art. -Nr.: HY-208727

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CDD-1282

CDD-1282 is a non-inhibitor of bone morphogenetic protein receptor type 2 (BMPR2), with no functional inhibitory activity against BMPR2 kinase. CDD-1282 can serve as a negative control for BMPR2 inhibitors.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3034215-93-2
Formel: C₂₅H₂₅N₅O₂
Molecular Weight:427.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDD-1282 Chemical Structure

CAS. Nr.: 3034215-93-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

CDD-1282 does not inhibit recombinant human BMPR2 kinase domain activity, with a K_iapp >1000 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3034215-93-2
Molecular Weight 427.50
Formel C₂₅H₂₅N₅O₂
SMILES

CNC(C1=CC2=C(N=C(N2[C@@H]3CC[C@@H](C(NC)=O)C3)C4=CC5=CC=NC=C5C=C4)C=C1)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. Journal of medicinal chemistry. 2023 Feb 09;66(3):2143-2160. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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