Cipamfylline
Cipamfylline is a PDE4 inhibitor that can cause PDE4A4 to accumulate in specific areas of the cell through interaction with the ubiquitin scaffolding protein p62. Cipamfylline can be used in the research of atopic dermatitis.
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- CAS. Nr.: 132210-43-6
- Formel: C13H17N5O2
- Molecular Weight:275.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 132210-43-6
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Molecular Weight 275.31
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Formel C13H17N5O2
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SMILES
O=C(N1CC2CC2)N(CC3CC3)C4=C(N=C(N)N4)C1=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Griffiths CE, et al. Randomized comparison of the type 4 phosphodiesterase inhibitor cipamfylline cream, cream vehicle and hydrocortisone 17-butyrate cream for the treatment of atopic dermatitis. Br J Dermatol. 2002 Aug;147(2):299-307. [Content Brief]
[2]. Day JP, et al. Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). J Med Chem. 2011 May 12;54(9):3331-47. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Cipamfylline Related Classifications
HY-139095 Related Classifications
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