Citreoindole
Citreoindole is a diketopiperazine metabolite isolated from a hybrid cell fusion of two strains of P. citreovirde that is cytotoxic in vitro against HeLa cells at 8.4 μM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 138655-14-8
- Formel: C29H28N4O4
- Molecular Weight:496.56
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
8.4 μg/mL
Compound: 707
|
Cytotoxicity against human HeLa cells assessed as reduction in cell growth measured after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell growth measured after 24 hrs by MTT assay
|
[PMID: 38181652] |
Chemical Information
-
CAS. Nr. 138655-14-8
-
Molecular Weight 496.56
-
Formel C29H28N4O4
-
SMILES
O=C([C@H](C[C@]1(O)[C@@](N[C@H](C2=CC=CC=C2)CC3=O)([H])N3C4=C1C=CC=C4)N5)N[C@@H](CC6=CC=CC=C6)C5=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
-
Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Citreoindole Related Classifications
HY-120190 Related Classifications
Powered by Bioz