CX-659S
CX-659S is an orally active 5-carboxamide uracil derivative. CX-659S can effectively inhibit lipid peroxidation (IC50 = 5.9 μM). CX-659S can reduce the infiltration of neutrophils and eosinophils. CX-659S inhibits the mRNA expression of pro-inflammatory cytokines IL-1β and TNF-α. CX-659S can be used for research on inflammatory conditions.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 204980-81-4
- Formel: C25H28N4O5
- Molecular Weight:464.51
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle TNF Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
IL-1β |
Chemical Information
-
CAS. Nr. 204980-81-4
-
Molecular Weight 464.51
-
Formel C25H28N4O5
-
SMILES
CC1=C2C(CC[C@](C)(O2)C(NC3=C(N(C4=CC=CC=C4)C(N(C3=O)C)=O)N)=O)=C(C(O)=C1C)C
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Tobe M, et al. Synthesis and biological evaluation of CX-659S and its related compounds for their inhibitory effects on the delayed-type hypersensitivity reaction. Bioorg Med Chem. 2000 Aug;8(8):2037-47. [Content Brief]
[2]. Goto Y, et al. Suppressive effect of topically applied CX-659S, a novel diaminouracil derivative, on the contact hypersensitivity reaction in various animal models. Int Arch Allergy Immunol. 2000 Dec;123(4):341-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CX-659S Related Classifications
HY-114908 Related Classifications
Powered by Bioz