DBCO-amine TFA
Based on 2 publication(s) in Google Scholar
DBCO-amine TFA is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.
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- CAS. Nr.: 2007915-94-6
- Formel: C20H17F3N2O3
- Molecular Weight:390.36
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) DBCO-amine TFA
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2007915-94-6
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Appearance Solid
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Molecular Weight 390.36
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Formel C20H17F3N2O3
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Color Light yellow to yellow
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SMILES
O=C(C(F)(F)F)O.O=C(CCN)N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Nanoscale Adv
2025 Aug 8;7(17):5421-5434. PMID: 40786133
Protokoll
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EdU Incorporation Assay (Click Chemistry-Based DNA Synthesis Measurement)
The EdU incorporation assay measures DNA synthesis by adding the thymidine analog 5-ethynyl-2′-deoxyuridine to cells or tissues, where it is incorporated into newly synthesized DNA during S phase. Incorporated EdU is detected by copper-catalyzed azide-alkyne cycloaddition, in which a fluorescent azide covalently reacts with the ethynyl group on EdU, allowing S-phase cells to be detected by fluorescence microscopy, flow cytometry, or high-content imaging. EdU detection does not require DNA denaturation or anti-BrdU antibody access, which preserves sample structure and improves compatibility with immunostaining and multiparameter cytometry compared with BrdU-based detection. EdU can be cytotoxic in a cell-type- and exposure-dependent manner, so pulse duration, concentration, and continuous-labeling designs should be validated for each cell type.
Reinheit & Dokumentation
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Data Sheet (242 KB)
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SDS (252 KB)
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Handling Instructions (2659 KB)
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DBCO-amine TFA Related Classifications
HY-W020546 Related Classifications
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