country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-114928

Copy Link Print Information

Deiodoamiodarone

(Synonyms: L 3937; Dideiodo Amiodarone)

Kundenbewertung

Based on 1 Customer Validation

Deiodoamiodarone (L 3937; Dideiodo Amiodarone) is an intermediate of amiodarone. Amiodarone is a potent calmodulin antagonist.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 96.0%
CAS. Nr.: 23551-25-9
Formel: C₂₅H₃₁NO₃
Molecular Weight:393.52

Speicherung:

Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Deiodoamiodarone Chemical Structure

CAS. Nr.: 23551-25-9

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Deiodoamiodarone (L 3937; Dideiodo Amiodarone) is an intermediate of amiodarone. Amiodarone is a potent calmodulin antagonist^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	33 nM Compound: 3, ddI-Ami	Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level	[PMID: 18752950]
HL-60	IC₅₀	2.77 μM Compound: 33m	Antiproliferative activity against human HL-60 cells measured after 24 hrs by MTT assay Antiproliferative activity against human HL-60 cells measured after 24 hrs by MTT assay	[PMID: 34605238]
MCF7	IC₅₀	5.26 μM Compound: 33m	Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay	[PMID: 34605238]
MDA-MB-231	IC₅₀	19.4 μM Compound: 33m	Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay	[PMID: 34605238]
U-937	IC₅₀	3.47 μM Compound: 33m	Antiproliferative activity against human U-937 cells measured after 24 hrs by MTT assay Antiproliferative activity against human U-937 cells measured after 24 hrs by MTT assay	[PMID: 34605238]

Chemical Information

CAS. Nr. 23551-25-9
Appearance Liquid (Density: 1.08 g/cm³)
Molecular Weight 393.52
Formel C₂₅H₃₁NO₃
Color Light yellow to yellow
SMILES

O=C(C1=CC=C(C=C1)OCCN(CC)CC)C2=C(OC3=CC=CC=C23)CCCC
Synonyms

L 3937; Dideiodo Amiodarone
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (254.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.5412 mL

12.7058 mL

25.4117 mL

5 mM

0.5082 mL

2.5412 mL

5.0823 mL

10 mM

0.2541 mL

1.2706 mL

2.5412 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. P Nokin, et al. Amiodarone is a potent calmodulin antagonist. Naunyn Schmiedebergs Arch Pharmacol. 1989 Apr;339(4):367-73. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.5412 mL	12.7058 mL	25.4117 mL	63.5292 mL
	5 mM	0.5082 mL	2.5412 mL	5.0823 mL	12.7058 mL
	10 mM	0.2541 mL	1.2706 mL	2.5412 mL	6.3529 mL
	15 mM	0.1694 mL	0.8471 mL	1.6941 mL	4.2353 mL
	20 mM	0.1271 mL	0.6353 mL	1.2706 mL	3.1765 mL
	25 mM	0.1016 mL	0.5082 mL	1.0165 mL	2.5412 mL
	30 mM	0.0847 mL	0.4235 mL	0.8471 mL	2.1176 mL
	40 mM	0.0635 mL	0.3176 mL	0.6353 mL	1.5882 mL
	50 mM	0.0508 mL	0.2541 mL	0.5082 mL	1.2706 mL
	60 mM	0.0424 mL	0.2118 mL	0.4235 mL	1.0588 mL
	80 mM	0.0318 mL	0.1588 mL	0.3176 mL	0.7941 mL
	100 mM	0.0254 mL	0.1271 mL	0.2541 mL	0.6353 mL

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

Deiodoamiodarone

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Deiodoamiodarone Related Classifications

HY-114928 Related Classifications