DS-1-38
Based on 1 Customer Validation
DS-1-38 is an EYA1 antagonist that blocks Sonic Hedgehog (SHH) signaling. EYA1 is a haloacid dehalogenase phosphatase and transcription factor that regulates tumorigenesis and proliferation in SHH medulloblastoma (SHH-MB).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.57%
- Formel: C21H18N2O3
- Molecular Weight:346.38
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Stem Cell Signaling Compound Library
HY-L017
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Wnt/Hedgehog/Notch Compound Library
HY-L020
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Differentiation Inducing Compound Library
HY-L038
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Anti-Breast Cancer Compound Library
HY-L074
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Liver Cancer Compound Library
HY-L101
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Anti-Colorectal Cancer Compound Library
HY-L103
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Cancer Stem Cells Compound Library
HY-L135
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Anti-Hematopathy Compound Library
HY-L171
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Gastric Cancer Compound Library
HY-L184
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Anti-Fibrosis Compound Library
HY-L185
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Anti-Brain Cancer Compound Library
HY-L188
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Cell Proliferation Compound Library
HY-L201
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High-Throughput Bioactive Compound Library
HY-L205
Biologische Aktivität
Chemical Information
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Appearance Solid
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Molecular Weight 346.38
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Formel C21H18N2O3
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Color White to off-white
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SMILES
CCC1=C(C2=C(C=CC(C3=CN(N=C3)C)=C2)O1)C(C4=CC=C(C=C4)O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 125 mg/mL (360.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8870 mL | 14.4350 mL | 28.8700 mL | 72.1751 mL |
| 5 mM | 0.5774 mL | 2.8870 mL | 5.7740 mL | 14.4350 mL | |
| 10 mM | 0.2887 mL | 1.4435 mL | 2.8870 mL | 7.2175 mL | |
| 15 mM | 0.1925 mL | 0.9623 mL | 1.9247 mL | 4.8117 mL | |
| 20 mM | 0.1444 mL | 0.7218 mL | 1.4435 mL | 3.6088 mL | |
| 25 mM | 0.1155 mL | 0.5774 mL | 1.1548 mL | 2.8870 mL | |
| 30 mM | 0.0962 mL | 0.4812 mL | 0.9623 mL | 2.4058 mL | |
| 40 mM | 0.0722 mL | 0.3609 mL | 0.7218 mL | 1.8044 mL | |
| 50 mM | 0.0577 mL | 0.2887 mL | 0.5774 mL | 1.4435 mL | |
| 60 mM | 0.0481 mL | 0.2406 mL | 0.4812 mL | 1.2029 mL | |
| 80 mM | 0.0361 mL | 0.1804 mL | 0.3609 mL | 0.9022 mL | |
| 100 mM | 0.0289 mL | 0.1444 mL | 0.2887 mL | 0.7218 mL |
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