Ebiratide TFA
Based on 1 Customer Validation
Ebiratide (HOE-427) TFA is an ACTH 4-9 derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy. Ebiratide TFA enhances acetycholine (ACh) metabolism in rat brain.
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- Reinheit : 99.04%
- Formel: C48H73N11O10S.xC2HF3O2
- Molecular Weight:996.23 (free base)
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electoconvulsive shock induced and Scopolamine (HY-N0296)-induced memory impairment in NMRI mice[1]
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Dosage:0.1-30 μg/kg
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Administration:s.c., single dose
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Result:Reduced the retention latency.
Chemical Information
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Appearance Solid
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Molecular Weight 996.23 (free base)
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Formel C48H73N11O10S.xC2HF3O2
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Color White to off-white
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Synonyms
HOE-427 TFA
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Sequence
{Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2}
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Sequence Shortening
{Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2}
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9(3):575-81. [Content Brief]
[2]. G Wiemer, et al. Neurochemical effects of the synthetic ACTH4-9-analog Hoe 427 (Ebiratide) in rat brain. Peptides. 1988 Sep-Oct;9(5):1081-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)