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Art. -Nr.: HY-184778

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Ethyl 2-fluorocinnamate

Ethyl 2-fluorocinnamate is a substituted ethyl cinnamate derivative with antifungal activity and weak sensitizing activity. Ethyl 2-fluorocinnamate inhibits mycelial growth of phytopathogenic fungi. Ethyl 2-fluorocinnamate can be used in studies related to plant fungal diseases.

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CAS. Nr.: 348-13-0
Formel: C₁₁H₁₁FO₂
Molecular Weight:194.20

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ethyl 2-fluorocinnamate Chemical Structure

CAS. Nr.: 348-13-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Ethyl 2-fluorocinnamate (compound A11) exhibits in vitro antifungal activity against Fusarium solani, Pyricularia grisea, Valsa mali, and Botryosphaeria dothidea with an average inhibition rate of 39.3% at 0.5 mM after 72 h of incubation^[1].
Ethyl 2-fluorocinnamate (compound 3b) is a weaker skin sensitizer than ethyl cinnamate, with an EC_1.5 of 44.0 μM, an EC₂ of 109.3 μM, an Imax of 2.8, and an IC₅₀ of 304.2 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 348-13-0
Molecular Weight 194.20
Formel C₁₁H₁₁FO₂
SMILES

O=C(/C=C/C1=C(F)C=CC=C1)OCC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Zhou K, et al. Bioactivity and structure-activity relationship of cinnamic acid esters and their derivatives as potential antifungal agents for plant protection. PloS one. 2017;12(4):e0176189. [Content Brief]

[2]. Charpentier J, et al. Effect of Fluorination on Skin Sensitization Potential and Fragrant Properties of Cinnamyl Compounds. Chemistry & biodiversity. 2018 Apr;15(4):e1800013. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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