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Art. -Nr.: HY-118120

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GEMSA

Name: GEMSA
Brand: MedChemExpress
SKU: HY-118120
Price: 485.00 USD
Availability: PreOrder

(Synonyms: 2-Guanidinoethylmercaptosuccinic acid)

GEMSA is a potent inhibitor of enkephalin convertase (K_i=8.8 nM). GEMSA elicites analgesia.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 98%
CAS. Nr.: 77482-44-1
Formel: C₇H₁₃N₃O₄S
Molecular Weight:235.26

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

GEMSA Chemical Structure

CAS. Nr.: 77482-44-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
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Calculators
Help & FAQs
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Biologische Aktivität

Beschreibung

GEMSA is a potent inhibitor of enkephalin convertase (K_i=8.8 nM). GEMSA elicites analgesia^[1].

IC₅₀ & Target

Encephalin convertase, K_i 值为8.8 nM.

In Vitro

GEMSA inhibits the activation of TAFI and porcine CBB^[1].
GEMSA can inhibit the prolongation of lysis time in recombinant BAP and does not lead to the lysis of APC fibronectin^[1].
GEMSA inhibits the prolongation of lysis time in porcine CPB, TAFI, and recombinant BAP, APC with the EC₅₀ values of 0.34 μM, 100μM, 115 μM, 90 μM respectively^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

GEMSA (ICV, 0.1μg/mg, every, 3days) results in a 75% increase in hypothalamic luteinizing hormone-releasing hormone and serum luteinizing hormone levels, and a 60% decrease in serum prolactin concentrations in rat^[3]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 77482-44-1
Appearance Solid
Molecular Weight 235.26
Formel C₇H₁₃N₃O₄S
Color White to off-white
SMILES

OC(C(SCCNC(N)=N)CC(O)=O)=O
Synonyms

2-Guanidinoethylmercaptosuccinic acid
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. B Przewlocka, et al. Analgesic and convulsant effects of guanidinoethylmercaptosuccinic acid (GEMSA)--a potent enkephalin convertase inhibitor. Neuropeptides. Nov-Dec 1986;8(4):359-65. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
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GEMSA

2-PMPA

2-MPPA

2-PMPA (Standard)

2-MPPA (Standard)

ZJ43

Mergetpa

2-Benzylsuccinic acid

CPA inhibitor

Carboxypeptidase G2 (CPG2) Inhibitor

GCPII-IN-1 TFA

2-Benzylsuccinic acid (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

GEMSA

2-PMPA

2-MPPA

2-PMPA (Standard)

2-MPPA (Standard)

ZJ43

Mergetpa

2-Benzylsuccinic acid

CPA inhibitor

Carboxypeptidase G2 (CPG2) Inhibitor

GCPII-IN-1 TFA

2-Benzylsuccinic acid (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

GEMSA Related Classifications

HY-118120 Related Classifications

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