UTP3 - UTP3 small subunit processome component Gene

Also Known as CRL1; CRLZ1; SAS10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57050

About UTP3

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,688,532-70,690,551 (from NCBI)

This gene has 1 transcript (splice variant), 174 orthologues and 1 paralogue.

Summary

Enables RNA binding activity. Predicted to be involved in brain development and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

UTP3 Products (1)

mRNA Protein Name
NM_020368.3 NP_065101.1 something about silencing protein 10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP3 Protein Structure

Sas10_Utp3

Sas10_Utp3: Sas10/Utp3/C1D family (229 - 310)

Sas10

Sas10: Sas10 C-terminal domain (404 - 478)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 479 a.a.
Protein Preferred Names Protein Names

something about silencing protein 10

  • UTP3 homolog

UTP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
UTP3 Q9NQZ2 C1orf131 Homo sapiens Q8NDD1-6
Y2H Array
32296183
Intra
UTP3 Q9NQZ2 C1orf131 Homo sapiens Q8NDD1-6
Y2H Prey Pooling
32296183
Intra
UTP3 Q9NQZ2 H1-4 Homo sapiens P10412
Crosslink
30021884
Intra
UTP3 Q9NQZ2 CDCA7L Homo sapiens Q96GN5
Validated Y2H
25416956
Intra
UTP3 Q9NQZ2 CDCA7L Homo sapiens Q96GN5
Y2H Prey Pooling
25416956
Intra
UTP3 Q9NQZ2 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
UTP3 Q9NQZ2 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
UTP3 Q9NQZ2 DVL3 Homo sapiens Q92997
Validated Y2H
25416956
Intra
UTP3 Q9NQZ2 DVL3 Homo sapiens Q92997
Y2H Array
25416956
Intra
UTP3 Q9NQZ2 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
UTP3 Q9NQZ2 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
UTP3 Q9NQZ2 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
UTP3 Q9NQZ2 H1-1 Homo sapiens Q02539
Crosslink
30021884
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Palmoplantar Keratoderma, Bothnian Type

  • PPKB

  • Diffuse Palmoplantar Keratoderma, Bothnian Type

  • Bothnian Type Palmoplantar Keratoderma

  • Keratoderma, Palmoplantar, Bothnian Type

  • Palmoplantar Keratoderma, Nonepidermolytic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15579 UTP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus UTP3 VGNC VGNC:36746
Felis catus UTP3 VGNC VGNC:66906
Canis familiaris UTP3 VGNC VGNC:48213
Macaca mulatta UTP3 VGNC VGNC:79434
Mus musculus UTP3 MGD MGI:1919230
Rattus norvegicus UTP3 RGD RGD:1308540
Others UTP3 NCBI