RPL18A - ribosomal protein L18a Gene
Also Known as L18A
Species: Homo sapiens
About RPL18A
This gene has 7 transcripts (splice variants) and 147 orthologues. Ubiquitous expression in ovary (RPKM 1039.7), lymph node (RPKM 680.9) and 25 other tissues.
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
RPL18A Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_000980.4 | NP_000971.1 | 60S ribosomal protein L18a |
RPL18A Protein Structure
Ribosomal_L18A: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A (7 - 130)
- 0
- 100
- 176 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
60S ribosomal protein L18a |
|
RPL18A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
RPL18A | Q02543 | RPL4 | Homo sapiens | P36578 | 28514442 | |
|
Intra
|
RPL18A | Q02543 | RPL4 | Homo sapiens | P36578 | 33961781 |
RPL18A Antibodies
| Art. -Nr. | Produktname | Anwendung | Reactivity |
|---|---|---|---|
| HY-P84473 | RPL18A Antibody (YA4170) | WB, IHC-P, ELISA | Human, Mouse |
| HY-P84473A | RPL18A Antibody (YA4170)(PBS only) | WB, IHC-P, ELISA | Human, Mouse |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Hepatitis C Virus |
|
|
| Omsk Hemorrhagic Fever |
|
|
| Brain Ependymoma |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | RPL18A | MGD | MGI:1924058 |
| Bos taurus | RPL18A | VGNC | VGNC:34112 |
| Rattus norvegicus | RPL18A | RGD | RGD:1302976 |
| Others | RPL18A | NCBI |