RPL18A - ribosomal protein L18a Gene

Also Known as L18A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6142

About RPL18A

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,859,910-17,863,319 (from NCBI)

This gene has 7 transcripts (splice variants) and 147 orthologues. Ubiquitous expression in ovary (RPKM 1039.7), lymph node (RPKM 680.9) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]

RPL18A Products (1)

mRNA Protein Name
NM_000980.4 NP_000971.1 60S ribosomal protein L18a

RPL18A Protein Structure

Ribosomal_L18A

Ribosomal_L18A: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A (7 - 130)

  • 0
  • 100
  • 176 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L18a

  • large ribosomal subunit protein eL20

RPL18A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
RPL18A Q02543 RPL4 Homo sapiens P36578 28514442
Intra
RPL18A Q02543 RPL4 Homo sapiens P36578 33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

RPL18A Antibodies

Art. -Nr. Produktname Anwendung Reactivity
HY-P84473 RPL18A Antibody (YA4170) WB, IHC-P, ELISA Human, Mouse
HY-P84473A RPL18A Antibody (YA4170)(PBS only) WB, IHC-P, ELISA Human, Mouse

Related Diseases

Diseases Alias
Hepatitis C Virus
  • Hepatitis C Virus, Susceptibility To

  • Hepatitis C Virus Infection, Response To Therapy Of

  • Hcv

  • Hcv, Susceptibility To

  • Hepatitis C Virus, Resistance To

  • Hepatitis C Virus, Response To Therapy Of

  • Resistance To Hepatitis C Virus

Omsk Hemorrhagic Fever
  • Ohf

  • Hemorrhagic Fever, Omsk

  • Ohf - [Omsk Haemorrhagic Fever]

  • Spring-Fall Haemorrhagic Fever

Brain Ependymoma
  • Ependymal Tumor Of Brain

  • Ependymoma Of Brain

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus RPL18A MGD MGI:1924058
Bos taurus RPL18A VGNC VGNC:34112
Rattus norvegicus RPL18A RGD RGD:1302976
Others RPL18A NCBI