RPL18A - ribosomal protein L18a Gene

Homo sapiens

Also known as L18A

Gene ID: 6142 | Gene type: protein coding

About RPL18A

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,859,910-17,863,319 (from NCBI)

This gene has 7 transcripts (splice variants) and 147 orthologues. Ubiquitous expression in ovary (RPKM 1039.7), lymph node (RPKM 680.9) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]

RPL18A Products(1)

mRNA	Protein	Name
NM_000980.4	NP_000971.1	60S ribosomal protein L18a

RPL18A Protein Structure

Ribosomal_L18A

0
100
176 a.a.

Protein Preferred Names

Protein Names

60S ribosomal protein L18a

large ribosomal subunit protein eL20

Related Diseases

Diseases

Alias

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To	Hepatitis C Virus Infection, Response To Therapy Of
Hcv	Hcv, Susceptibility To
Hepatitis C Virus, Resistance To	Hepatitis C Virus, Response To Therapy Of
Resistance To Hepatitis C Virus

Omsk Hemorrhagic Fever

Ohf	Hemorrhagic Fever, Omsk
Ohf - [Omsk Haemorrhagic Fever]	Spring-Fall Haemorrhagic Fever

Brain Ependymoma

Ependymal Tumor Of Brain

Ependymoma Of Brain

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12170	RPL18A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RPL18A	MGD	MGI:1924058
Bos taurus	RPL18A	VGNC	VGNC:34112
Rattus norvegicus	RPL18A	RGD	RGD:1302976

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