Hydroxycotinine-d3
Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease.
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- CAS. Nr.: 1311275-10-1
- Formel: C10H9D3N2O2
- Molecular Weight:195.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1311275-10-1
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Unlabeled CAS 34834-67-8
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Molecular Weight 195.23
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Formel C10H9D3N2O2
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SMILES
O[C@@H](C1=O)C[C@](C2=CN=CC=C2)([H])N1C([2H])([2H])[2H]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 30 mg/mL (153.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
Verweise
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1222 mL | 25.6108 mL | 51.2216 mL | 128.0541 mL |
| 5 mM | 1.0244 mL | 5.1222 mL | 10.2443 mL | 25.6108 mL | |
| 10 mM | 0.5122 mL | 2.5611 mL | 5.1222 mL | 12.8054 mL | |
| 15 mM | 0.3415 mL | 1.7074 mL | 3.4148 mL | 8.5369 mL | |
| 20 mM | 0.2561 mL | 1.2805 mL | 2.5611 mL | 6.4027 mL | |
| 25 mM | 0.2049 mL | 1.0244 mL | 2.0489 mL | 5.1222 mL | |
| 30 mM | 0.1707 mL | 0.8537 mL | 1.7074 mL | 4.2685 mL | |
| 40 mM | 0.1281 mL | 0.6403 mL | 1.2805 mL | 3.2014 mL | |
| 50 mM | 0.1024 mL | 0.5122 mL | 1.0244 mL | 2.5611 mL | |
| 60 mM | 0.0854 mL | 0.4268 mL | 0.8537 mL | 2.1342 mL | |
| 80 mM | 0.0640 mL | 0.3201 mL | 0.6403 mL | 1.6007 mL | |
| 100 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.2805 mL |
Hydroxycotinine-d3 Related Classifications
HY-113239S Related Classifications
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