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Art. -Nr.: HY-161032

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IP6K2-IN-1

Name: IP6K2-IN-1
Brand: MedChemExpress
SKU: HY-161032
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC₅₀ value of 0.55 μM. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors.

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Reinheit: 99.47%
CAS. Nr.: 2926679-10-7
Formel: C₁₆H₁₀O₇
Molecular Weight:314.25

Speicherung:

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

IP6K2-IN-1 Chemical Structure

CAS. Nr.: 2926679-10-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC₅₀ value of 0.55 μM^[1]. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors^[1].

IC₅₀ & Target^[1]

IP6K2

In Vitro

IP6K2-IN-1 (Compound 20s) shows IC₅₀ value of 2.87 µM against IP6K1 resulting 5.22-fold IC₅₀ ratio of IP6K1/IP6K2 and IC₅₀ value of 3.56 µM against IP6K3, resulting 6.47-fold IC₅₀ ratio of IP6K3/IP6K2^[1].
IP6K2-IN-1 failed to reduce IP7 levels in HCT116 cells, indicating low cell permeability^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2926679-10-7
Appearance Solid
Molecular Weight 314.25
Formel C₁₆H₁₀O₇
Color Yellow to brown
SMILES

OC1=C(O)C=C(C(C(O)=C(C2=CC(C(O)=O)=CC=C2)O3)=O)C3=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Myunghwan Ahn, et al. Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2193866. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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