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Art. -Nr.: HY-129473

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JCP678

JCP678 is a selective inhibitor of Staphylococcus aureus serine hydrolase (FphF). JCP678 blocks the labeling of FphF by serine-reactive activity probes. JCP678 is applicable to research related to Staphylococcus aureus infections.

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CAS. Nr.: 82422-62-6
Formel: C₁₄H₁₂FNO₄S
Molecular Weight:309.31

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

JCP678 Chemical Structure

CAS. Nr.: 82422-62-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

FphF

In Vitro

JCP678 (1 μM; 60 min) potently and selectively inhibits the ~28 kDa serine hydrolase FphF in live Staphylococcus aureus ATCC35556 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 82422-62-6
Molecular Weight 309.31
Formel C₁₄H₁₂FNO₄S
SMILES

O=C(OCC1=CC=CC=C1)NC2=CC=CC(S(=O)(F)=O)=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Lentz CS, et al. Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP). Nature chemical biology. 2018 Jun;14(6):609-617. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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