Jun13296
Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model.
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- CAS. Nr.: 3063566-68-4
- Formel: C30H34N6O
- Molecular Weight:494.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM)
Chemical Information
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CAS. Nr. 3063566-68-4
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Molecular Weight 494.63
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Formel C30H34N6O
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SMILES
O=C(N[C@@H](C1=CC(C2=CN(C)N=C2)=NC3=CC=CC=C13)C)C4=CC(N5C[C@@](N6C)([H])CC[C@@]6([H])C5)=CC=C4C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)