KHKI-01215
Based on 1 Customer Validation
KHKI-01215 is an inhibitor for NUAK2 with an IC50 of 0.052 μM. KHKI-01215 inhibits the proliferation of cancer cell SW480 with an IC50 of 3.16 μM, induces apoptosis in SW480. KHKI-01215 inhibits the YAP signaling pathway.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.78%
- CAS. Nr.: 3077585-25-9
- Formel: C24H26F3IN6O
- Molecular Weight:598.40
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Stem Cell Signaling Compound Library
HY-L017
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Wnt/Hedgehog/Notch Compound Library
HY-L020
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Transcription Factor-Targeted Library
HY-L090
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Anti-Liver Cancer Compound Library
HY-L101
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Anti-Colorectal Cancer Compound Library
HY-L103
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Anti-Pulmonary Fibrosis Compound Library
HY-L125
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Cancer Stem Cells Compound Library
HY-L135
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Cell Death Library
HY-L162
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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Cell Proliferation Compound Library
HY-L201
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High-Throughput Bioactive Compound Library
HY-L205
Alle YAP Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Chemical Information
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CAS. Nr. 3077585-25-9
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Appearance Solid
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Molecular Weight 598.40
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Formel C24H26F3IN6O
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Color White to off-white
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SMILES
FC(C1=CC(NC2=NC=C(I)C(OC3=CC=CC(N(C)C)=C3)=N2)=CC=C1N4CCN(C)CC4)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 125 mg/mL (208.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6711 mL | 8.3556 mL | 16.7112 mL | 41.7781 mL |
| 5 mM | 0.3342 mL | 1.6711 mL | 3.3422 mL | 8.3556 mL | |
| 10 mM | 0.1671 mL | 0.8356 mL | 1.6711 mL | 4.1778 mL | |
| 15 mM | 0.1114 mL | 0.5570 mL | 1.1141 mL | 2.7852 mL | |
| 20 mM | 0.0836 mL | 0.4178 mL | 0.8356 mL | 2.0889 mL | |
| 25 mM | 0.0668 mL | 0.3342 mL | 0.6684 mL | 1.6711 mL | |
| 30 mM | 0.0557 mL | 0.2785 mL | 0.5570 mL | 1.3926 mL | |
| 40 mM | 0.0418 mL | 0.2089 mL | 0.4178 mL | 1.0445 mL | |
| 50 mM | 0.0334 mL | 0.1671 mL | 0.3342 mL | 0.8356 mL | |
| 60 mM | 0.0279 mL | 0.1393 mL | 0.2785 mL | 0.6963 mL | |
| 80 mM | 0.0209 mL | 0.1044 mL | 0.2089 mL | 0.5222 mL | |
| 100 mM | 0.0167 mL | 0.0836 mL | 0.1671 mL | 0.4178 mL |
KHKI-01215 Related Classifications
HY-162709 Related Classifications
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