Lofendazam

Lofendazam is a major metabolite of Arfendazam. Lofendazam acts as a positive allosteric modulator/partial agonist of GABAa receptor, with IC50 values of 10.1 nM and 9.1 nM in bovine cerebral cortex and bovine cerebellum, respectively; its in vivo ED50 via oral administration is 233 µmol/kg.

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  • CAS. Nr.: 29176-29-2
  • Formel: C15H13ClN2O
  • Molecular Weight:272.73
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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