MDI-403
MDI-403 is a retinoic acid receptor (RAR) agonist with an EC50 value of less than 1 μM. MDI-403 exhibits significant antiviral activity against SARS-CoV-2, and can dose-dependently inhibit the expression of viral nucleoprotein (NP) and reduce the proportion of infected cells. MDI-403 mainly acts during the virus invasion stage. MDI-403 can be used in research on anti-SARS-CoV-2.
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- CAS. Nr.: 127471-94-7
- Formel: C29H36O4
- Molecular Weight:448.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 127471-94-7
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Molecular Weight 448.59
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Formel C29H36O4
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SMILES
C(=C/C(=C/C=C/C(=C\C(OCC(=O)C1=CC=C(OC)C=C1)=O)/C)/C)\C=2C(C)(C)CCCC2C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MDI-403 Related Classifications
HY-W816575 Related Classifications
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Keywords
- MDI-403
- 127471-94-7
- MDI403
- MDI 403
- RAR/RXR
- SARS-CoV
- Retinoic acid receptors
- Retinoid X receptors
- SARS coronavirus
- SARS-CoV-2
- drug repurposing
- ReFRAME library
- antiviral compounds
- RAR agonist
- high-throughput screening
- viral replication inhibition
- Vero E6 cells
- dose-response
- synergy with remdesivir
- Inhibitor
- inhibitor
- inhibit