(-)-Conocarpan
(-)-Conocarpan is a natural compound that can be isolated from various species of Krarneria.
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- CAS. Nr.: 56319-02-9
- Formel: C18H18O2
- Molecular Weight:266.33
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
19.5 μM
Compound: 7
|
Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method
Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method
|
[PMID: 21800856] |
| HEK293 | IC50 |
>20 μM
Compound: 7
|
Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay
Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay
|
[PMID: 21800856] |
Chemical Information
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CAS. Nr. 56319-02-9
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Appearance Solid
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Molecular Weight 266.33
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Formel C18H18O2
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Color White to off-white
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SMILES
OC1=CC=C([C@@H]2OC3=CC=C(/C=C/C)C=C3[C@H]2C)C=C1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (263 KB)
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SDS (398 KB)
- English - EN (398 KB)
- Français - FR (398 KB)
- Deutsch - DE (398 KB)
- Norwegian - NO (398 KB)
- Español - ES (398 KB)
- Swedish - SV (398 KB)
- Italian - IT (398 KB)
- Korean - KR (398 KB)
- Portuguese - PT (398 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)