oLOX
oLOX is a fluorescent activity reporter. oLOX can be activated by lysyl oxidase family (LOXF) enzymes, which in turn releases a luciferin fluorescent product that reports LOXF enzyme activity. After oLOX is activated in in vitro fibrotic lung tissues, the fluorescence intensity increases, enabling real-time detection of fibrotic activity. oLOX can be used in studies related to pulmonary fibrosis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2241794-11-4
- Formel: C26H26N2O5
- Molecular Weight:446.50
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
oLOX (10 μM; 2 h) exhibits up to a 300% increase in fluorescence in aged human lung tissue homogenate, with significant signal amplification detected after 30 min and signal plateauing between 50 min and 2 h[1].
oLOX (200 μM) generates a significant increase in fluorescent signal in fibrotic regions of ventilating ex vivo asinine lung detectable via FCFM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 2241794-11-4
-
Molecular Weight 446.50
-
Formel C26H26N2O5
-
SMILES
NCCCOC1=CC2=C(C3(C4=C(O2)C=C(C=C4)OCCCN)OC(C5=C3C=CC=C5)=O)C=C1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
oLOX Related Classifications
HY-D3208 Related Classifications
Powered by Bioz